Pictured to the right is the basic design of one of my microfluidic devices. I fabricated them using a simple PDMS process – creating a mold using photolithography of SU-8 on a silicon wafer. An even simpler way to make molds is to use a stereolithography company or 3D printing.
The macroscale interface to the microfluidic devices were assembled using HPLC equipment. We used a Harvard Apparatus syringe pump to drive flow through the chip – controlled by LabView code communicating through a RS232 connection.