Publications

79 entries « 2 of 2 »

2018

Workman, Rachael E; Myrka, Alexander M; Wong, William G; Tseng, Elizabeth; Welch, Kenneth C; Timp, Winston

Single-molecule, full-length transcript sequencing provides insight into the extreme metabolism of the ruby-throated hummingbird Archilochus colubris Journal Article

In: GigaScience, vol. 7, iss. 3, pp. giy009, 2018.

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Xiong, Tina; Rohm, Dahlia; Workman, Rachael E; Roundtree, Lauren; Novina, Carl D; Timp, Winston; Ostermeier, Marc

Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria Journal Article

In: PLoS One, vol. 13, no. 12, pp. 1-18, 2018.

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2017

Lee, Isac; Rasoul, Bejan A; Holub, Ashton S; Lejeune, Alannah; Enke, Raymond A; Timp, Winston

Whole genome DNA methylation sequencing of the chicken retina, cornea and brain Journal Article

In: Scientific Data, vol. 4, iss. 1, pp. 1-8, 2017, ISSN: 2052-4463.

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Xiong, Tina; Meister, Glenna E; Workman, Rachael E; Kato, Nathaniel C; Spellberg, Michael J; Turker, Fulya; Timp, Winston; Ostermeier, Marc; Novina, Carl D

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases Journal Article

In: Scientific Reports, vol. 7, iss. 1, pp. 1-14, 2017, ISSN: 2045-2322.

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Kandathil, Abraham J; Breitwieser, Florian P; Sachithanandham, Jaiprasath; Robinson, Matthew; Mehta, Shruti H; Timp, Winston; Salzberg, Steven L; Thomas, David L; Balagopal, Ashwin

Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs Journal Article

In: Annals of Internal Medicine, vol. 167, no. 1, pp. 1–7, 2017, ISSN: 1539-3704.

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Simpson, Jared T; Workman, Rachael E; Zuzarte, P C; David, Matei; Dursi, L J; Timp, Winston

Detecting DNA cytosine methylation using nanopore sequencing Journal Article

In: Nature Methods, vol. 14, no. 4, pp. 407–410, 2017, ISSN: 1548-7091.

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Luo, Ruibang; Zimin, Aleksey; Workman, Rachael; Fan, Yunfan; Pertea, Geo; Grossman, Nina; Wear, Maggie P; Jia, Bei; Miller, Heather; Casadevall, Arturo; Timp, Winston; Zhang, Sean X; Salzberg, Steven L

First Draft Genome Sequence of the Pathogenic Fungus Lomentospora prolificans (formerly Scedosporium prolificans) Journal Article

In: G3: Genes, Genomes, Genetics, vol. 7, no. 11, pp. 3831–3836, 2017.

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Credle, Joel J; Itoh, Christopher Y; Yuan, Tiezheng; Sharma, Rajni; Scott, Erick R; Workman, Rachael E; Fan, Yunfan; Housseau, Franck; Llosa, Nicolas J; Bell, Robert W; Miller, Heather; Zhang, Sean X; Timp, Winston; Larman, Benjamin H

Multiplexed analysis of fixed tissue RNA using Ligation in situ Hybridization Journal Article

In: Nucleic Acids Research, vol. 45, no. 14, pp. e128–e128, 2017.

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2016

Norris, Alexis L; Workman, Rachael E; Fan, Yunfan; Eshleman, James R; Timp, Winston

Nanopore sequencing detects structural variants in cancer Journal Article

In: Cancer Biology & Therapy, vol. 17, no. 3, pp. 246–253, 2016, ISSN: 1555-8576.

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2014

Timp, Winston; Nice, Allison M; Nelson, E M; Kurz, V; McKelvey, K; Timp, Gregory

Think Small: Nanopores for Sensing and Synthesis Journal Article

In: IEEE Access, vol. 2, pp. 1396–1408, 2014, ISSN: 2169-3536.

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Timp, Winston; Bravo, Hector Corrada; McDonald, Oliver G; Goggins, Michael; Umbricht, Chris; Zeiger, Martha; Feinberg, Andrew P; Irizarry, Rafael A

Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors Journal Article

In: Genome Medicine, vol. 6, no. 8, pp. 61, 2014, ISSN: 1756-994X.

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2013

Kurz, Volker; Nelson, Edward M; Perry, Nicolas; Timp, Winston; Timp, Gregory

Epigenetic Memory Emerging from Integrated Transcription Bursts Journal Article

In: Biophysical Journal, vol. 105, no. 6, pp. 1526–1532, 2013, ISSN: 0006-3495.

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Timp, Winston; Feinberg, Andrew P

Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host Journal Article

In: Nature Reviews Cancer, vol. 13, no. 7, pp. 497–510, 2013, ISSN: 1474-1768.

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2012

Nelson, Edward M; Kurz, Volker; Shim, Jiwook; Timp, Winston; Timp, Gregory

Using a Nanopore for Single Molecule Detection and Single Cell Transfection Journal Article

In: The Analyst, vol. 137, no. 13, pp. 3020–3027, 2012, ISSN: 0003-2654.

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Timp, Winston; Comer, Jeffrey; Aksimentiev, Aleksei

DNA base-calling from a nanopore using a Viterbi algorithm Journal Article

In: Biophysical Journal, vol. 102, no. 10, pp. L37–39, 2012, ISSN: 1542-0086.

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2011

McDonald, Oliver G; Wu, Hao; Timp, Winston; Doi, Akiko; Feinberg, Andrew P

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition Journal Article

In: Nature Structural & Molecular Biology, vol. 18, no. 8, pp. 867–874, 2011, ISSN: 1545-9985.

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Hansen, Kasper Daniel; Timp, Winston; Bravo, Héctor Corrada; Sabunciyan, Sarven; Langmead, Benjamin; McDonald, Oliver G; Wen, Bo; Wu, Hao; Liu, Yun; Diep, Dinh; Briem, Eirikur; Zhang, Kun; Irizarry, Rafael A; Feinberg, Andrew P

Increased methylation variation in epigenetic domains across cancer types Journal Article

In: Nature Genetics, vol. 43, no. 8, pp. 768–775, 2011, ISSN: 1061-4036.

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2010

Timp, Winston; Mirsaidov, Utkur M; Wang, Deqiang; Comer, Jeff; Aksimentiev, Aleksei; Timp, Gregory

Nanopore Sequencing: Electrical Measurements of the Code of Life Journal Article

In: IEEE Transactions on Nanotechnology, vol. 9, no. 3, pp. 281–294, 2010, ISSN: 1536-125X.

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2009

Timp, Winston; Mirsaidov, Utkur; Matsudaira, Paul; Timp, Gregory

Jamming prokaryotic cell-to-cell communications in a model biofilm Journal Article

In: Lab on a Chip, vol. 9, no. 7, pp. 925–934, 2009, ISSN: 1473-0197.

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Timp, Winston; Levchenko, Andre; Feinberg, Andrew P

A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction Journal Article

In: Cell Cycle (Georgetown, Tex.), vol. 8, no. 3, pp. 383–390, 2009, ISSN: 1551-4005.

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Mirsaidov, U; Timp, W; Zou, X; Dimitrov, V; Schulten, K; Feinberg, A P; Timp, G

Nanoelectromechanics of methylated DNA in a synthetic nanopore Journal Article

In: Biophysical Journal, vol. 96, no. 4, pp. L32–34, 2009, ISSN: 1542-0086.

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2008

Mirsaidov, Utkur; Scrimgeour, Jan; Timp, Winston; Beck, Kaethe; Mir, Mustafa; Matsudaira, Paul; Timp, Gregory

Live cell lithography: using optical tweezers to create synthetic tissue Journal Article

In: Lab on a Chip, vol. 8, no. 12, pp. 2174–2181, 2008, ISSN: 1473-0197.

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Mirsaidov, Utkur; Timp, Winston; Timp, Kaethe; Mir, Mustafa; Matsudaira, Paul; Timp, Gregory

Optimal optical trap for bacterial viability Journal Article

In: Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics, vol. 78, no. 2 Pt 1, pp. 021910, 2008, ISSN: 1539-3755.

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Timp, Winston; Matsudaira, Paul

Chapter 14: Electron microscopy of hydrated samples Journal Article

In: Methods in Cell Biology, vol. 89, pp. 391–407, 2008, ISSN: 0091-679X.

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2007

Kaneda, Atsushi; Wang, Chiaochun J; Cheong, Raymond; Timp, Winston; Onyango, Patrick; Wen, Bo; Iacobuzio-Donahue, Christine A; Ohlsson, Rolf; Andraos, Rita; Pearson, Mark A; Sharov, Alexei A; Longo, Dan L; Ko, Minoru S H; Levchenko, Andre; Feinberg, Andrew P

Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 52, pp. 20926–20931, 2007, ISSN: 1091-6490.

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Zeskind, Benjamin J; Jordan, Caroline D; Timp, Winston; Trapani, Linda; Waller, Guichy; Horodincu, Victor; Ehrlich, Daniel J; Matsudaira, Paul

Nucleic acid and protein mass mapping by live-cell deep-ultraviolet microscopy Journal Article

In: Nature Methods, vol. 4, no. 7, pp. 567–569, 2007, ISSN: 1548-7091.

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2006

Akselrod, G M; Timp, W; Mirsaidov, U; Zhao, Q; Li, C; Timp, R; Timp, K; Matsudaira, P; Timp, G

Laser-guided assembly of heterotypic three-dimensional living cell microarrays Journal Article

In: Biophysical Journal, vol. 91, no. 9, pp. 3465–3473, 2006, ISSN: 0006-3495.

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Timp, Winston; Watson, Nicki; Sabban, Alon; Zik, Ory; Matsudaira, Paul

Wet electron microscopy with quantum dots Journal Article

In: BioTechniques, vol. 41, no. 3, pp. 295–298, 2006, ISSN: 0736-6205.

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1999

O’Malley, M L; Timp, G L; Timp, W; Moccio, S V; Garno, J P; Kleiman, R N

Electrical simulation of scanning capacitance microscopy imaging of the pn junction with semiconductor probe tips Journal Article

In: Applied Physics Letters, vol. 74, no. 24, pp. 3672–3674, 1999, ISSN: 0003-6951.

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79 entries « 2 of 2 »